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SOLID PHASE EXTRACTION SYSTEM

speX Series Solid Phase Extraction System for 48, 96 and 144 Positive Pressure Sample Processing Systems by Takahe Analytical Instruments Solid phase extraction — SPE is a chromatographic technique used to prepare samples for subsequent analysis by removing interfering substances that may be present. This is done either by retaining the substance of interest and washing off everything else or by retaining the interfering substances and eluting the product of interest. Takahe Analytical Instruments® specifically meets the requirements of BA/BE labs in the CRO industry for the extraction requirements. We offer a range of models of the Nitrogen Evaporators and Solid Phase Extraction Systems based on the application of the industry. Our systems offer seamless solutions for sample preparation of large batch volumes with the 100 and 144 position Nitrogen Evaporators and 96 and 144 sample Solid Phase Extraction using Positive Pressure Manifold systems. Unique features Aluminium body with high grade long-lasting powder coating. Light on hand Two Hand Operation for safety Dual flow settings - for extraction and drying. Inter-changeable racks for multiple size test tubes. Inter-changeable racks for 144 position Nitrogen Evaporator. Easy to use test tube tray. Even column processing times. Reproducible analyte recoveries. Lesser pre-process preparations. Convenient direct waste disposal. Dependable After Sales Service. Supplied with DQ/IQ/OQ/PQ documentation. Standard Warranty - One-year. Takahe Difference At Takahe we are constantly innovating to meet the requirements of the analyst to make her life a little simpler with fewer errors and faster processing. Like the Bio-eVAP 100 and 144 that we introduced in the market, we have enhanced the SPE 144 to make it simple for observing the elution of the large samples processed. This avoids arm fatigue as well as eliminates errors. Special Features of speX 144 series Positive Pressure Manifold has been first conceptualized, designed and manufactured by Takahe Analytical Instruments. The SPLIT cartridge rack and interchangeable COLLECTION Racks are our offerings in this process. Special features of speX 144 series Positive Pressure Manifold conceptualized, designed and manufactured first by Takahe Analytical Instruments. 144 split - cartridge rack *As a rack split into 3 section of 48, visibility of eluted samples is similar to the 48 position SPE system. *Lighter on the arms and easy handling *Can be loaded on benchtop without contaminating cartridges. Inter-changeble collection racks for 144 series *144 Collection rack fits the Bio-eVap nitrogen evaporator of Takahe Analytical Instruments *Evaporation rack from Bio-eVap fits into SPE *Saves transfer time *Eliminates errors

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LABORATORY SHAKER

Shakers are laboratory equipment that provide a gentle oscillating motion to mix, agitate, or incubate samples in a variety of vessels such as tubes, flasks, and microplates. They are commonly used in biological, chemical, and pharmaceutical research, as well as in industrial applications such as food processing, cosmetics manufacturing, and environmental testing. Shakers are one of the integral equipment of a biotechnology and pharmaceutical laboratory. Hence, they require reliable and efficient equipment for sample preparation and analysis. Our shakers are designed to take your samples to the next level for analysis. Hence, we built in many features that make them different from the regular shakers available in the market. Product Features • Available with compliance documents. • User adjustable orbit length (amplitude). • Time, RPM, Pulse Time (ON time as well as OFF time, both are user selectable. • BLDC high wattage motor is used for low maintenance, and noise. • Gentle start ensures there is no sample spillage. • Easy Installation and operation • Aluminium Sample Platform for rust control • Incubator temperature selectable -controlled chamber • Easy Mounting and Removing of labware design • Maintenance Free Product Specifications RPM 10 to 300 (in Real Time) Timer 999 Minutes Pulse Yes Pulse On Off Time 999 Seconds Control Microprocessor Display 4-line 20-Character LCD White Backlite Supplied with Power cord / Rack Covers / Manual / QC Report Included QC docs with attached traceability Electric Requirement 230 V 50 Hz Single Phase 3 Amps Compliance Documents IQ OQ PQ can be provided on site Dimension LXWXH 50 X 20 X 26 CMS Product Weight 8 Kgs

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LABORATORY MIXER

For extraction, especially for liquid-liquid extraction for compounds that are sensitive and vortex mixing cannot be used a Multitube Mixer with large sample capacity works very well as it saves time and meets compliance requirements. Our flagship products have been satisfactorily accepted by end-users. To serve all the industry needs we have also in our offering, various instruments often used for in different labs including, Clinical Research, Food, Soil and pesticide testing and other such needs. With several hundred installations across India and overseas, Takahe Analytical Instruments have established their products with CROs, agriculture & environment industry, food industry, testing labs and educational institutions. Specifications & Technical Details: Model name: Mixer - Rotary Disc Type Sample Disk : 1 RPM : 10 to 100 Time Setting : 1 to 999 min Pulse Mode : Yes ON OFF Time Selectable : 1 to 999 Seconds Maintenance Free BLDC Motor : Wattage 130 Smallest Footprint : 50 X 20 cms Power : 120 to 230 Volts Other details: Controls Microprocessor RPM & Time display 4-line 20-Character LCD White Backlite Supplied with Disk with Test Tube Clamps Power cord Manual, QC docs with attached traceability certificates Rating 120 to 230 volts Features: • 50mL Test Tube 15 Positions • 15mL Test Tube 20 Positions • 4mL Test Tube 45 Positions • Can be supplied with temperature-controlled chamber • Inter-changeable test tube racks for multiple size test tubes testing SPECIAL FEATURE: - • Customization of Sample Disk for different glassware.

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LABORATORY MIXER

Multitube Mixers: For extraction, specially for liquid-liquid extraction for compounds that are sensitive and vortex mixing cannot be used a Multitube Mixer with large sample capacity works very well as it saves time and meets compliance requirements. Our flagship products have been satisfactorily accepted by end-users. To serve all the industry needs we have also in our offering, various instruments often used for in different labs including, Clinical Research, Food, Soil and pesticide testing and other such needs. With several hundred installations across India and overseas, Takahe Analytical Instruments have established their products with CROs, agriculture & environment industry, food industry, testing labs and educational institutions. Specifications & Technical Details: Max no. Of samples 180 (4mL - Ria Vials) 144 (15mL – Tarson Tubes) 39 (50mL – Tarson Tube) Number of Rack Stations 2 RPM 10 to 100 Time Setting 1 to 999 min Pulse Mode Yes ON OFF Time Selectable 1 to 999 Seconds Maintenance Free BLDC Motor Wattage 130 Smallest Footprint 50 X 20 cms Power 120 to 230 Volts Other details: Controls Microprocessor RPM & Time display 4-line 20-Character LCD White Backlite Supplied with Rack Holders 2 Nos with clamps Power cord Manual, QC docs with attached traceability certificates Rating 120 to 230 volts Features: • Aluminium Sample Platform for rust control • Rack Mounting Home positions for easy mounting • Can be supplied with temperature-controlled chamber • Inter-changeable test tube racks for multiple size test tubes testing SPECIAL FEATURE: - • Customisation of Racks platforms for different kind of glassware Certifications: ISO Certification to Takahe Analytical Instruments - ISO 9001:2015 Quality Management System for following scope of activities: Manufacturing of Analytical Instruments and Related Software Development.

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NITROGEN EVAPORATOR

Product range for Nitrogen Evaporator : Nitrogen Evaporators are used to prepare samples for analysis. In a lot of industries, such as food, biotechnology, analytical chemistry, petroleum, and environmental science, nitrogen evaporators dry and concentrate samples so they can be tested with mass spectrometry, gas chromatography, and HPLC. It is also possible to use heat in conjunction with nitrogen blowdown to eliminate moisture from samples after they have been loaded into the nitrogen evaporator. Various Nitrogen evaporators are used such as one wet or dry baths, whether it needs hood space, and whether it provides heat and nitrogen blowdown to evaporate the samples. These come as 15 positions, 50 positions, High Volume 9 positions, End-point evaporators, 100 position Nitrogen Evaporators and 144 position Evaporators Sample preparation is an important part of the analysis using instruments like LCs, GCs, LC-MS, GC-MS, Elisa Readers. Part of sample preparation is concentration using Nitrogen Evaporators and Nitrogen Concentrator Sample Concentrators. Nitrogen Evaporators are also called N2 Evaporator or Sample Concentrator. Concentration of non-heat sensitive samples uses evaporation as a method to achieve best results. This concentrated sample gives better results when analysed. With individual laboratories using different samples, methods and analytical techniques, Takahe Analytical Instruments® are pioneers in Nitrogen Evaporators and Concentrators in India to meet the needs of the user and their applications. The product range allows evaporating samples from well-plates, test tubes, End points tubes, flasks and beakers. The product also is extended to evaporate large sample batches used in Phase II and Phase IV trials – typically the 100 position and 144 sample Nitrogen Evaporator Our forte lies in offering the user what he requires. Customisation of the product is done on specific customer needs. This customisation is undertaken after a feasibility study to ensure there is no compromise on the end result. Once a method is set, the automated operation of the SpeedoVap, Min-eVap, Bio-eVap, Duo-eVap and other range of our Nitrogen Evaporators and Concentrators frees up critical lab resources for other productive needs. Features of Speedovap N2 Evaporators : 1.Unattended operation for up to 50 samples 2.Different interchangeable N2 Evaporators racks available for tube sizes from 1.5 mL to 30 mL 3.Controlled water bath adjustable from ambient to 80 °C 4.Built-in nitrogen regulator 5.Different process and alert alarms 6.LED display for better visibility under fume hood 7.Convenient size—no hood space required 8.Exhaust open to atmosphere or within Fume Hood 9.Easy to use water drain pump 10.Small footprint FAQ's What is the lead time for delivery after placing order for N2 evaporator? - Our nitrogen evaporators are typically ex-stock and dispatched immediately. However, if there is a specific rack requirement, we will require 2-3 weeks time to meet the customized requirement. How Much Nitrogen Is Required to Evaporate Samples in A Nitrogen Evaporator? - Our 144-position nitrogen evaporator requires only 220 -250 lpm of Nitrogen (1.6 lpm) and our Speedovap 50 position requires 150lpm Nitrogen (3 lpm per nozzle) What sets your Nitrogen Concentrator Sample Evaporators apart from others in the market? - At Takahe Analytical Instruments, we take pride in several factors that distinguish our Nitrogen Evaporators from other brands in the market: 1. Decades of Experience 2. In-House Design and Manufacturing 3.Optimum Nitrogen Utilization 4.Commitment to Customer Service How are samples concentrated in the Nitrogen Evaporator? - Concentration of non-heat sensitive samples can be achieved through evaporation using nitrogen evaporators, also known as N2 evaporators or sample concentrators, as part of the sample preparation process. This is achieved using wet or dry baths, and with or without heat and nitrogen blowdown options. Concentrated samples often provide better analysis results, especially when using instruments like LCs, GCs, LC-MS, GC-MS, and Elisa Readers.

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NITROGEN EVAPORATOR

A game-changer in the CRO industry, the Bio-eVap 144 Position Nitrogen Evaporator is our significant contribution to large-scale bio-analytical studies. Designed to process 100 to 144 small volume samples simultaneously, this innovative evaporator ensures reproducibility, reduced Nitrogen consumption, and hands-free operation through cutting-edge technologies. Key Features: - Unattended operation with 144 sample capacity. - Dual pressure settings to eliminate contamination risk during the evaporation process. - In-built alarms with customizable settings, including over-temperature alert and door open sensor. - Interchangeable racks for different tube sizes. - Controlled water bath adjustable from ambient to 70°C. - Built-in nitrogen regulator for efficient operation. - LED display for better visibility under a fume hood. - Compact size for large sample processing in the same space as a 50-sample processor. - Removable nozzle tips for easy sonication, with no realignment required. - Option for fixed nozzle tips. - Safety features include audio and display alarms, auto-stop on door open, and exhaust options. Unique Features: - Set program cannot be changed once the process has begun. - Specially identified row selector switches for flow control. - Compatible rack for the Bio-eVap 144 can be used with TAKAHE SPE speX 144. - Printing and data storage facility available on request. Conclusion: Experience unparalleled efficiency and convenience in large-scale bio-analytical studies with the Bio-eVap 144 Position Nitrogen Evaporator. This cutting-edge system not only enhances reproducibility but also ensures contamination-free processing, making it an indispensable tool in the advancement of CRO research. Feature for Bio-eVap 100 position Nitrogen Evaporator :- Maximum Number of Samples/positions : 100 (Matrix: 10 X 10) Sample Volume : 1.5 mL, 4 mL, Upto 15 mL Rack Supplied : Any one Rack listed based on requirement. (additional racks can be ordered separately) Water Bath Temperature : Ambient to 70°C. Gas Supply Requirements : Inlet pressure 100 psi Gas Regulator : Manually adjustable Gas Flow required : 200 LPM Gas Gauge Range : 0 – 56 psi | 0-4 kg | 0- 3.9 bar Technology : Vortexing Dimensions (WxDxH) in cm : 37 X 70 X 25 | Open Door Ht: 68 cm Net Weight : 17 kg Shipping Weight : 30 kg Feature for Bio-eVap 144 position Nitrogen Evaporator :- Maximum Number of Samples/positions : 144 (Matrix: 12 X 12) Sample Volume : 1.5 mL, 4 mL, Upto 15 mL Rack Supplied : Any one Rack listed based on requirement. (additional racks can be ordered separately) Water Bath Temperature : 1 min to 9. 50 hours/indefinite Gas Supply Requirements : Inlet pressure 100 psi Gas Regulator : Initial and Final Pressure Manually set Gas Flow required : 260 LPM Gas Gauge Range : 0 – 56 psi | 0-4 kg | 0- 3.9 bar Technology : Vortexing Dimensions (WxDxH) in cm : 57 X 57 X28 | Open Door Ht: 68 cm Net Weight : 18.5 kg Shipping Weight : 35 kg Common Features : Gas Control : Each Manifold can be turned ON as required. No multiple punches on Keyboard Fume Extraction : Exhaust In-built, Vented out. Duct hose provided Power Requirements : 230 VAC at 50 Hz (110 VAC – available on request) Certifications : 2004/22/EC Measuring Instruments Directive. 2014/35/EU Low Voltage Directive 2009/105/EC Simple Pressure Vessels. Test Tubes Capacity in mL Dimensions in mm (OD X H) 1.5 mL Eppendorf Micro Centrifuge tubes 4 mL Ria vials 11.5 X 75 mm 15 mL 16 mm X 120 mm 15 mL 15 mL Tarson tube (only for BV 100)

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LABORATORY SHAKER

Wrist Action Separatory Funnel Shaker Takahe’s new addition to the sample preparation instruments is the Wrist Action Shaker also commonly known as the Separating Funnel Shaker. This shaker is efficient in shaking reagents of various kinds of materials under same control parameters. It is suitable for organic, inorganic chemical, medical, and pharmaceutical research, extraction & development of media, and waste water analysis. Up to 6 Funnels of different capacity (from 50 mL to 250 mL) can be fixed simultaneously with specially designed adjustable funnel holder. The BLDC motor is low noise and maintenance free, the acceleration is electronically buffered avoiding jerks, the RPM is dynamically displayed and the stop at the home position makes it easy to add solvents and release gas generated during the shaking process. Technical Specifications Maximum Number of Samples- 6 Sample volume- 50 mL to 1000 mL Max no. of samples / station- 3 Stroke per Minute- 15 to 150 Time- 1 to 999 Minutes Pulsed- On / Off Times can be set 0 to 999 Seconds Stroke Angle- Adjustable in 5 steps Mechanically Other Details Control Microprocessor Keys Tactile Switches BLDC Motor Noiseless and maintenance free Wattage 120 Watts Voltage 110 to 220 Volts

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NITROGEN GENERATOR

A Nitrogen generator produces nitrogen gas from compressed air. Nitrogen is a colorless gas that makes up 78% of the Earth's atmosphere. It is non-flammable and non-reactive, making it an ideal gas for many industrial and commercial applications. Productive time of analysts and users spent in follow-up for cylinder procurement, change and daily installation of cylinders are eliminated. In operations, cylinders having high cylinder pressure creates a safety issue which is also now addressed with the Nitrogen Generator. With high requirement of Nitrogen for the Nitrogen evaporator and Nitrogen Solvent concentrator, the Nitrogen Generator is a simple solution for tedious logistics, high cost of cylinders and vendor dependency. PSA Nitrogen Generator PSA nitrogen generators use a pressure swing adsorption (PSA) process to separate nitrogen from oxygen in the air. PSA Nitrogen Generator uses two towers filled with carbon molecular sieve (CMS). The "online" tower is filled with compressed air that flows through the CMS. Nitrogen passes through the CMS while oxygen and other trace gases are absorbed. Once a pre-set time has passed, the on-line tower automatically switches to regenerative mode, venting contaminants. In contrast to ordinary activated carbon, carbon molecular sieve has a much smaller range of pore openings. Nitrogen molecules are too large to enter the CMS, so oxygen penetrates the pores and we get pure Nitrogen. Our nitrogen generators are delivered as complete systems, complete with air filters and automatic controls to hook up to a compressed air supply. Start up your PSA Nitrogen Generator by switching it on, and you're ready to start. Also, maintenance is easy. PSA Nitrogen Generator filters only need to be changed once every six to twelve months, depending on your usage. Intelligent Control Our in-house developed software process controller generates the output of Nitrogen by optimising the functions to increase compressor life and reduce running costs over long periods of use. Switching to Nitrogen Generator is a wise decision Recover your operating expense by investing in your capital. Clean particulate free nitrogen with certified purity. Nitrogen supplied on demand. No dependency on vendors and maintenance man-power. Eliminate periodic logistics of cylinder procurement. Features of Nitrogen Generator Silent and seamless Nitrogen gas supply to your lab. Compact non-obstructive design with the option of wall-mounting and free up precious space. In-built service features to indicate timely routine maintenance. Automatically switches to standby mode when Nitrogen is not required - thereby reducing wear & tear of the compressor. Advantages of Nitrogen Generator? Reduced costs: Nitrogen generators can be a more cost-effective option than buying nitrogen gas from a supplier. Increased safety: On-site nitrogen generation can help to improve safety by reducing the need for nitrogen gas cylinders, which can be a safety hazard if handled by untrained personnel Increased convenience: Nitrogen generators can provide a convenient and reliable source of nitrogen gas, which can be used on demand. FAQ- What makes us different from other Nitrogen Generator companies? There are several factors that make us different from other Nitrogen Generator. One factor is our experience. We have been designing, manufacturing, and selling Nitrogen Generator for over 4 years. With discussions with our users we have a deep understanding of their needs helping us to provide them with high-quality products and services. Our Nitrogen Generator has a dedicated design team and manufacturing team. We have a strict quality control system and professional testing equipment and we have a strong R&D team. Another factor that makes us different is our commitment to customer service. We have a team of highly trained and experienced customer service representatives who are available to answer any questions that our customers may have. We also offer a 100% satisfaction guarantee on all of our products and services.

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