Use of Solid Phase Extraction in Leather Industry : Solid Phase Extraction (SPE) is a commonly used sample preparation technique in the leather industry for the analysis of various compounds. It involves the selective adsorption of target compounds onto a solid sorbent material, followed by elution and analysis. The leather industry utilizes SPE in the analysis of various chemicals and contaminants in raw materials, processing chemicals and finished products. SPE is particularly useful in the detection of organic contaminants such as polycyclic aromatic hydrocarbons (PAHs), which can be harmful to human health and the environment. SPE is used in the leather industry to extract and concentrate PAHs from various samples, including leather dust, wastewater and finished leather products. The extracted PAHs are then analyzed using techniques such as gas chromatography-mass spectrometry (GC-MS) or high-performance liquid chromatography (HPLC). SPE is also used to extract and purify dyes and pigments used in the leather industry. Dyes and pigments can be selectively adsorbed onto solid sorbents, leaving impurities and unwanted compounds behind. The purified dyes and pigments can then be eluted and used in leather processing. In addition to the detection and purification of contaminants and dyes, SPE is also used in the analysis of tannins in the leather industry. Tannins are natural compounds found in many plant species, and they play an important role in the tanning process. SPE can be used to extract and concentrate tannins from various sources, including plant extracts and leather samples. In summary, solid phase extraction is a valuable tool in the leather industry for the analysis of various compounds. It is particularly useful in the detection and purification of organic contaminants, dyes, pigments, and tannins. SPE can improve the accuracy and sensitivity of analytical techniques, helping the leather industry to produce high-quality products that are safe for human use and the environment.